Preconception
Introduction
The term preconception refers to the period leading up to a pregnancy, from the decision to have a baby to becoming pregnant (conceiving).
A healthy pregnancy
Preconception care involves taking good care of yourself before you become pregnant, by ensuring that you eat healthily and exercise regularly.
Make sure that you are up to date with vaccinations, such as rubella (the virus that causes German measles) and varicella (which causes chickenpox and shingles).
If you are trying to conceive, your GP can provide you with further information and advice to ensure the best possible health for you and your baby.
In cases where a pregnancy is not planned, a woman will only begin to monitor her health in relation to the baby after she is already pregnant. However, for couples who plan their pregnancies, preconception care can help them to make the necessary changes well in advance.
How long will it take to get pregnant?
The length of time that it takes to become pregnant (conceive) is different for everyone but, on average, for every 100 couples who have sex two or three times a week:
- 30 will conceive within one month
- 60 will conceive within six months
- 85 will conceive within one year
The remaining couples will take longer and some may need medical help to conceive. A small number of couples (about 5%) may not be able to conceive at all if one partner or both is infertile.
The type of contraception that you have been using does not usually affect your ability to conceive or how long it takes to happen.
However, women who have been using the progestogen-only injection may find that their usual fertility is delayed, and that they cannot conceive for up to a year after their last injection. Other methods of contraception should not have an effect on your fertility once you stop using them.
If you have had a miscarriage in the past, you still have a good chance of having a healthy pregnancy and baby. However, if you have had three or more miscarriages in a row, your GP may refer you to a gynaecologist (a specialist in reproductive healthcare). They will be able to determine whether or not your miscarriages are being caused by an underlying health problem.
Health assessment
Health assessment
Lifestyle assessment
Preconception care involves an assessment of lifestyle, health and fitness by a healthcare professional, in order to identify areas for improvement.
Areas that the assessment may focus on include:
- an unhealthy diet
- lack of exercise
- other factors that can harm an unborn baby, such as smoking and illegal drug use
Preconception care focuses mainly on the woman's health, but there are changes that the man can make as well. For example, men are advised to cut down on the amount of alcohol that they drink, and to avoid smoking.
This is because drinking and smoking have been shown to decrease the quality of a man’s sperm, which could reduce the chances of their partner conceiving.
Controlling pre-existing conditions
Another important part of preconception care is to ensure that any chronic (long-term) health problems that you have are controlled as effectively as possible before you become pregnant.
Chronic health problems, such as diabetes, epilepsy and asthma, can cause an increased risk of complications developing for both mother and baby during pregnancy and labour (when the baby is being born). For example, having poorly controlled diabetes can mean that you have a higher risk of miscarriage (loss of the pregnancy during the first 23 weeks).
Risk assessment
During the preconception assessment, genetically inherited conditions (those that are passed on from the parents) can be identified. Couples with a high risk of having a baby with a genetic condition can be given support and advice.
Some of the conditions that can be passed on to a baby from its parents are:
- cystic fibrosis, where internal bodily secretions become thicker and hinder the function of organs, such as the lungs and digestive system
- sickle-cell anaemia, a condition that affects the ability of red blood cells to carry oxygen around the body
- Huntingdon's disease, a condition that causes the nerve cells in the brain to deteriorate
Being aware of the risks will enable couples to make informed choices when planning their pregnancy.
Recommendations
Recommendations
Depending on how healthy your lifestyle normally is, when you become pregnant you may need to make changes to your diet, drinking habits and the amount of exercise that you do. You will also need to ensure that you are up-to-date with all of your required vaccinations and screening tests.
To ensure that your pregnancy goes as smoothly as possible, and that your baby is as healthy as possible, it is important that you take good care of yourself while you are pregnant, and follow the self-care guidelines outlined below.
Diet
While you are pregnant it is important that you maintain a healthy, balanced diet that includes food from all of the main food groups. This will help both you and your baby to stay healthy during your pregnancy. You should aim to eat:
- at least five portions of fruit and vegetables a day
- four to six portions of carbohydrates each day, such as rice, pasta, potatoes, cereals and bread
- at least one portion of pasteurised dairy products a day, such as cheese, milk and yoghurt
- three portions of protein from foods such as meat, fish, eggs, poultry and pulses
You should also make sure that you drink plenty of fluids each day (at least two litres) because this will help your body to get rid of toxins, as well as preventing nausea and constipation. Water and fruit juices are good choices.
When trying to get pregnant, you should avoid eating swordfish, shark and marlin. It is also advisable to limit how much tuna fish you eat to two tuna steaks or four medium-sized cans of tuna a week. This is because these types of fish contain high levels of mercury, which can potentially harm the development of a baby's nervous system.
See the Health A-Z topic on Diet for more information and advice about eating a healthy, balanced diet.
Food hygiene
Your GP and midwife can give you information about food hygiene and how to avoid bacterial food infections that could harm you or your baby. Salmonella and listeriosis are two common bacterial food infections. You should avoid eating:
- soft cheeses, such as brie and blue-veined cheese (there is no risk with processed cheese, cottage cheese or hard cheeses such as cheddar)
- vegetable or meat pâté
- any food that could contain raw or partially cooked eggs, such as mayonnaise
- raw or partially cooked meat, particularly poultry
Toxoplasmosis is an infection that is caused by undercooked or uncooked cured meats, such as salami, from contaminated soil or water, and from the faeces of infected cats. It is an infection that could potentially cause problems for your unborn baby.
Folic acid
Taking folic acid supplements before and during pregnancy can reduce the risk of your baby being born with a neural tube defect (NTD). Neural tube defects, such as spina bifida, adversely affect the growth and development of your baby's brain and spinal cord.
You should take 0.4mg (400 micrograms) of folic acid daily if you are trying to conceive, and you should continue to take it until your 12th week of pregnancy, while your baby's spine develops.
Folic acid supplements are available over the counter at pharmacies. As well as taking folic acid supplements, you can also add foods that are high in folic acid to your diet, such as green leafy vegetables and breads and cereals.
You have a higher risk of having a baby affected by a NTD if:
- either you, or your partner, has a NTD
- you have had a previous pregnancy affected by a NTD
- you have coeliac disease (a condition that is caused by a sensitivity to gluten)
- you are diabetic
- you are taking antiepileptic medication
If you have a high risk of having a baby with a NTD, a higher daily dose of folic acid may be recommended. In this case, your GP or midwife will be able to recommend an appropriate dose of folic acid for you.
Alcohol
Drinking alcohol while you are pregnant can harm your unborn baby. Binge drinking during early pregnancy is thought to be particularly harmful. Heavy drinking during pregnancy is associated with low birthweight and many other serious birth defects, such as heart problems and delayed development.
It is best to avoid drinking any alcohol if you are planning a pregnancy. You should also avoid drinking alcohol while you are pregnant. If you are trying to conceive, you may be unaware that you are pregnant until several weeks into the pregnancy, so you should stop drinking alcohol before any damage can be done.
If you want to drink alcohol while pregnant, to minimise your baby's risk do not have more than one or two units, once or twice a week. One unit of alcohol is approximately equal to one small glass of wine, half a pint of ordinary-strength bitter or lager, or a pub measure (25ml) of spirits.
It is important never to get drunk while you are pregnant. If you feel you are unable to reduce your levels of drinking on your own, you should visit your GP who will be able to refer you to a specialist for help.
Caffeine
Consuming too much caffeine during pregnancy can lead to your baby having a lower than normal birth weight. It can also increase your baby’s risk of developing health problems later in life and may also increase the chances of miscarriage (losing the baby during the first 23 weeks of pregnancy).
The Food Standards Agency (FSA) recommends a maximum daily intake of 200mg of caffeine during pregnancy. As a guide, 200mg is equivalent to:
- two mugs of instant coffee
- one mug of filter coffee
- two mugs of tea
- five cans of cola
- four (50g) bars of plain chocolate (caffeine in milk chocolate is roughly half of that in plain chocolate)
You should check with your pharmacist before taking any cold-and-flu remedies because some of them contain caffeine.
Exercise
Regular, moderate exercise is highly recommended for most pregnant woman. Exercise can help boost your energy levels, and keeping in shape will help to prepare for labour by increasing stamina and muscle strength.
Thirty minutes of moderate exercise a day – for example, swimming or walking – is recommended for most pregnant women. Your GP or midwife can advise you further about specific types of exercise that are appropriate for you.
Sports such as scuba-diving and any activities that put you at risk of falling, such as horse-riding, are not recommended while you are pregnant because they may put the baby’s development at risk.
Body weight
Before becoming pregnant, you should try to get as close as possible to the ideal weight for your height and build.
If you are overweight or obese you should try to lose weight before trying to conceive. Women who are overweight or obese are more likely to need a Caesarean section (where the baby is removed through an incision in the abdomen), and they are at higher risk of having a stillborn baby.
Overweight or obese women also have a higher risk of developing pre-eclampsia, a condition where pregnant women develop high blood pressure (hypertension), as well as protein in their urine and fluid retention. Pre-eclampsia is usually mild, but in rare cases it can cause serious harm to the mother and growth problems in the unborn baby.
You are overweight if your body mass index (BMI) is between 25 and 29.9. You are obese if your BMI is 30 or more. To find out your BMI, use the healthy weight calculator.
Visit your GP if you are overweight or obese and you are planning to become pregnant. They will be able to advise you about the most effective and safest way to lose weight.
Vitamin A
Avoid taking vitamin A supplements while you are pregnant because they may cause abnormalities to develop in your unborn baby. Also avoid eating liver because it is high in vitamin A.
Over-the-counter medications
Wherever possible, avoid using over-the-counter (OTC) medicines while you are pregnant. This is because not all OTC medicines have been proven safe for pregnant women to use. Check with your GP or pharmacist if you are unsure.
If you need pain relief while you are pregnant, or if you have a high temperature, paracetamol is usually recommended at the lowest possible effective dose. Depending on the stage of your pregnancy, ibuprofen may also be recommended.
For more information, see Can I take ibuprofen when I’m pregnant? (Common Health Questions).
Complementary medicines
It is not advisable to take complementary medicines while you are trying to conceive, or while you are pregnant. Many complementary medicines are unlicensed, and there is not enough evidence to confirm that they are safe for both you and your baby.
For more information, see Are complementary therapies safe during pregnancy? (Common Health Questions).
Advice for men
Many of the recommendations above also apply to men.
Vaccinations and screening
Vaccinations and screening
Vaccinations and screening
If you are planning a pregnancy, make sure that you are up-to-date with vaccinations such as rubella (German measles) and varicllea (chickenpox).
Vaccinations
All women who wish to become pregnant should be vaccinated against the rubella virus. You may have already been vaccinated against rubella when you were younger, but your GP may want to carry out a test to check your immunity.
If you are not immune, you may have to wait up to a month after being vaccinated before trying to conceive.
If you have never had chickenpox or shingles, you may need to be vaccinated against the varicella the virus before you can become pregnant.
However, it is unlikely that you will need vaccinating unless there is a risk of you coming into contact with carriers of the virus, such as healthcare workers.
If you do need to be vaccinated, you may have to wait up to six weeks after the vaccine before trying to conceive.
Similarly, women who are likely to contract hepatitis B may need to be vaccinated against the condition before they can conceive. You may need a hepatitis B vaccination if:
- You are a healthcare worker.
- You have a chronic (long-term) condition, such as kidney or liver disease.
- You come into close contact with someone who has hepatitis B.
- You have many different sexual partners.
- You use intravenous drugs (injected into a vein).
Cervical screening
If you are planning a pregnancy and you are due to have a cervical screening test, you will need to have it before you conceive. This is because pregnancy can make the results of a cervical screening test difficult to interpret.
See the Health A-Z Cervical screening test to find out more.
Risks during preconception
There are several factors that can pose a risk to your health during pregnancy. It is a good idea for you to be aware of these risks before you conceive.
In some cases, you will need to change your own habits to ensure that you have a smooth, trouble-free pregnancy, and your baby is as healthy as possible.
In other cases, the risks to your baby are less easy to control, for example, health conditions that are passed on through the parents’ genes. Preconception assessments can help to identify couples with a high risk of having a baby with an inherited condition, such as cystic fibrosis or sickle-cell anaemia.
Smoking
Smoking while pregnant can cause numerous health problems for your unborn baby, including an increased risk of miscarriage, early birth and a reduced birth weight. There is also evidence that women who smoke while they are pregnant are more likely to have babies that die of sudden infant death syndrome (SIDs), a condition that is also known as cot death.
If you want to have a baby and you smoke, it is very important that you stop smoking before you become pregnant. Do not wait until after you have conceived before giving up because you may not know that you are pregnant until you are several weeks into the pregnancy and, by smoking, you will have already harmed your baby.
Visit your GP if you are finding it difficult to stop smoking, or if you are already pregnant and you are still smoking. They will refer you to a smoking cessation service who will be able to advise you about the best ways to quit. The Health A-Z topic about Smoking, quitting also provides information and advice.
You can also call the confidential NHS pregnancy smoking helpline (0800 169 9169) to speak to a trained advisor who will be able to provide you with useful advice and information. The helpline is open every day, from 12pm to 9pm.
If you are already pregnant and you want to stop smoking, it is best to try to give up without using nicotine replacement therapy (NRT) such as patches and chewing gum. This is because these methods still expose your baby to nicotine, which may have similar, harmful effects to smoking.
However, if you have tried unsuccessfully to stop smoking without using NRT, your GP may advise you to use it. The exposure to nicotine will harm you and your baby less than the exposure to tobacco smoke, which contains higher levels of nicotine and many other harmful toxins.
Illegal drugs
Women who are planning to become pregnant should not take illegal drugs. If you have been taking drugs, carry on using contraception until you are able to stop.
Women who use illegal drugs while they are pregnant seriously endanger their baby's health, and increase the risks of miscarriage and low birth weight. Studies have shown that women who use cocaine or heroin during their pregnancy are twice as likely as women to have a premature baby compared with women who do not use these drugs.
It has also been shown that woman who use cocaine during pregnancy are more likely to have a child with behavioural problems. Premature and low birth weight babies have an increased risk of lasting health problems, such as mental health problems, cerebral palsy (where brain damage affects movement and coordination) and even death. In some cases, illegal drug use can cause your baby to have a brain haemorrhage (bleeding in the brain).
See your GP if you need help and support to give up using illegal drugs. If you have been using intravenous drugs (drugs injected through a vein), you will be offered testing for hepatitis B, hepatitis C and HIV.
Hazardous substances or radiation
If you are trying to conceive, you should make it a habit to check the warning labels of any products that contain chemicals, such as cleaning products. Ask your GP if you are unsure about any particular product.
If you have a job that involves working closely with hazardous substances, infections, or radiation it is a good idea to tell your employer that you are planning to become pregnant. Your employer is legally obliged to minimise the risk to you and your baby of any potentially harmful substances.
However, if you would rather not tell your employer that you want to become pregnant, you can obtain information about the risks of specific substances by visiting the Health and Safety Executive website.
Inherited disorders
Some health problems and conditions are inherited, which means that they are passed down to a baby from the genes of its parents. Inherited disorders include:
- sickle-cell anaemia, where red blood cells cannot carry oxygen around your body properly
- cystic fibrosis, where the lungs and digestive system are unable to work effectively
- Huntingdon's disease, a condition which causes the brain to gradually deteriorate.
See the Health A-Z topics about sickle-cell anaemia, cystic fibrosis and Huntingdon’s disease for more information about these conditions.
If you want to become pregnant, you should be offered screening for blood conditions to find out if you carry any blood diseases that could be passed on to your baby. Your GP will take a blood sample and you will need to fill out a family of origin questionnaire, which identifies people from high-risk populations.
Couples with a personal or family history of an inherited genetic condition, or those who have had a previously affected pregnancy, can be referred for genetic screening and counselling. Ideally, this should be carried out before you become pregnant, so it is important to see your GP before you start trying to conceive your baby.
Older women
A woman's risk of having a baby with a chromosomal condition, such as Down's syndrome, increases as she becomes older. If you are 35 to 40, your chances of having a baby with Down's syndrome are one in 270, compared with one in 1,500 if you are 20 to 30 years old..
The risk increases to one in 100 for women over 40. and one in 50 for women over 45. Your risk also increases if you have had a previous pregnancy that was affected by Down's syndrome.
There is no test to show whether or not you will have a baby with a chromosomal condition before you become pregnant. However, antenatal testing can be carried out during your pregnancy to estimate the likelihood of your baby being affected.
This may be carried out using an alpha-fetoprotein test, which measures the levels of alpha-fetoprotein (AFP) in your blood. If your AFP levels are low, it could indicate that your baby has Down's syndrome.
If you have a particularly high risk of having a baby affected by a chromosomal condition, or you have had an AFP test that shows that your levels of AFP are low, you may be able to have a diagnostic test that can show for definite whether or not your baby has a chromosomal condition.
Diagnostic testing can be carried out using amniocentesis, chorionic villus sampling (CVS) or by testing a sample of your baby's blood. The sample is collected from a vein in the umbilical cord using a thin needle that is passed through your abdomen.
Amniocentesis testing and chorionic villus sampling (CVS) are carried out in the same way, but amniocentesis takes samples of amniotic fluid (the fluid that surrounds and protects your baby in the womb), and CVS takes a sample of placenta, for testing. These tests carry a small risk of harming your baby, but this is very rare and only occurs in around 1-2% of cases.
Chronic health conditions
Chronic health conditions
If you have a long-lasting (chronic) health problem, it is very important that it is effectively treated and controlled before you become pregnant. Chronic health problems that can affect pregnancy include:
- epilepsy
- heart disease
- high blood pressure (hypertension)
- blood clots
- kidney disease
- sickle-cell anaemia
- thalassaemia
- diabetes
- thyroid disease
- rheumatoid arthritis
- asthma
- depression
- bipolar disorder and schizophrenia
If you have a chronic health problem, you should visit your GP after you have decided to have a baby. They will be able to refer you for a full assessment of your condition and any medication that you are taking. Never stop taking prescription medication unless advised to do so by a healthcare professional.
Carry on using contraception until your assessment is complete because some medications can be harmful to an unborn baby. You may need to continue using contraception until your condition is under control, or until your medication has been changed to one that will not harm your baby.
See below for further information about the chronic health problems listed above, and the preconception care for each one:
Epilepsy
If you have epilepsy, you are at increased risk of experiencing complications during pregnancy and labour. But you still have a 90% chance of having a normal pregnancy and labour, even with antiepileptic medication.
Your GP can refer you to a specialist who will assess your condition and medication, and change it if necessary. Some antiepileptic medications can be harmful to an unborn baby, and may cause heart abnormalities or facial defects. It is important to continue to use effective methods of contraception until a full assessment has been carried out by a specialist.
Women who are taking anti-epileptic medication are more at risk of having a baby with a neural tube defect (NTD), such as spina bifida (a conditon where your baby's brain and spinal cord do not develop properly). You will need to take 5mg of folic acid supplements daily before you become pregnant, until your 12th week of pregnancy.
Heart disease
Having a heart condition can make pregnancy unsafe for both mother and baby. The more severe your heart condition is, the more likely it is that you will experience complications.
If your heart condition is mild and you have few, or no, symptoms, you will have a relatively low risk of developing complications during your pregnancy. However, if your heart condition is severe, and your symptoms are continuous, it may not be safe for you to conceive unless your heart function can be improved. Before trying to conceive, your GP should refer you to a cardiologist (a heart specialist) to assess the level of risk to you and your unborn baby.
It is important to use effective methods of contraception until a specialist says it is safe not to.
High blood pressure (hypertension)
Women with high blood pressure (hypertension) are more likely to develop pre-eclampsia during pregnancy.
Pre-eclampsia is a condition where pregnant women develop high blood pressure, as well as protein in their urine, and fluid retention. It is usually mild, but in rare cases it can cause serious harm to the mother and growth problems to the unborn baby. If you have high blood pressure, your pregnancy will need to be closely monitored to ensure that pre-eclampsia can be controlled, should it occur.
Your GP can refer you to a cardiologist (a heart specialist) for an assessment of your condition. They may decide to change the medication you are taking.
Blood clots in the veins
If you have had a blood clot in a vein (venous thromboembolism), or if someone in your family has had one, your GP may recommend that you are screened to determine the likelihood that you will develop blood clots before you become pregnant.
If the blood test reveals that you have an increased risk of developing a blood clot because you have a family history of thrombophilia, or if you have previously had deep vein thrombosis (DVT) (where a blood clot develops in a deep vein), or a pulmonary embolism (a blood clot in the lung), you will need to be referred for specialist advice. A pulmonary embolism can be very dangerous for the mother during pregnancy.
If you are taking warfarin to help thin your blood, you will need to change to a different medication, such as heparin, because warfarin can be very harmful to your unborn baby.
Kidney disease
Having kidney disease can increase your chances of having a premature baby. If you have kidney disease, your GP may refer you to a specialist for an assessment. You should carry on using contraception until the assessment is complete. If you have had a kidney transplant, you may have to wait to conceive for up to two years after your operation.
Sickle-cell anaemia
If you have sickle-cell anaemia, you are more at risk of having a baby with a neural tube defect (NTD), such as spina bifida. If you have sickle-cell anaemia, you should already be taking 5mg of folic acid supplements every day as part of your treatment, and it is important to keep this up during pregnancy.
Your GP can refer you to a haematologist (a specialist in blood diseases), who can assess your condition and monitor your pregnancy. Carry on using contraception until your assessment is complete.
Thalassaemia
If you have thalassaemia, a condition which can cause anaemia (where the blood is unable to carry enough oxygen due to a low red blood cell count), you will need to take 5mg of folic acid supplements every day throughout your pregnancy.
However, women who have the condition without symptoms only need to take the recommended 400 micrograms of folic acid daily. If you are a carrier of thalassaemia, your partner will need to be tested to see if they are also a carrier.
If you have thalassaemia before becoming pregnant, you should be referred to a haematologist (a specialist in blood diseases) for an assessment.
Diabetes
If you have diabetes, your condition needs to be controlled as well as possible before you become pregnant. Otherwise, you have an increased risk of miscarriage or having a baby with serious health problems. Therefore, continue to use contraception until your condition is under control.
Your GP may refer you to a preconception diabetes clinic or to your diabetes care team (a team of diabetes specialists who you should have been assigned when you were diagnosed with the condition) for an assessment.
Having diabetes also means that you are at increased risk of having a baby with a neural tube defect (NTD), such as spina bifida. You will therefore need to take 5mg of folic acid supplements daily, starting before you are pregnant if possible, up until your 12th week of pregnancy.
For more information, see Is my baby at risk if I’m pregnant and have diabetes? (Common Health Questions).
Thyroid disease
If you have a thyroid disease (either an underactive or overactive thyroid) before becoming pregnant, your condition needs to be as closely controlled as possible. You will also need to be closely monitored during your pregnancy.
If you have an underactive thyroid (hypothyroidism), you should inform your GP as soon as you think that you may be pregnant because your medication dosage may need to be altered.
If you have an overactive thyroid (hyperthyroidism), you may have to complete a course of treatment before you can conceive. For women with hyperthyroidism who want to conceive in the next few years, surgery to remove all, or part, of the thyroid gland may be the best option.
Rheumatoid arthritis
If you have rheumatoid arthritis, you should be referred to a rheumatologist (a specialist in arthritis) for an assessment of your condition and medication. Your medication will need to be changed if you have been taking disease-modifying anti-rheumatic drugs (DMARDs), as these can harm your unborn baby. You will need to continue using contraception until the DMARDs have completely left your system, which may take up to several months.
Asthma
If you have asthma, your condition must be well controlled before you become pregnant, and you must continue to use your medication as prescribed throughout your pregnancy. If you have severe asthma, your GP may refer you to a specialist chest physician, who can assess and monitor your condition.
Depression
Having depression will only affect your pregnancy if you are taking medication for your condition. This is because some anti-depressants can harm an unborn baby. Your GP can review your medication and change it if necessary.
If your have mild depression, your GP may recommend a break from your medication while you are pregnant. However, do not stop taking anti-depressants unless you are advised to do so by a healthcare professional.
If your depression is severe, your GP can refer you to a psychiatrist (a mental health specialist) who can assess your condition and medication.
Bipolar disorder and schizophrenia
If you have bipolar disorder or schizophrenia, your GP will refer you to a psychiatrist who can assess your condition and any medication that you are taking. Continue to use contraception until the assessment is complete, and do not stop taking your medication unless you are advised to do so.
Some women with bipolar disorder may be taking antiepileptic medication for their condition. If this is the case, you have a higher risk of having a baby with a neural tube defect (NTD), such as spina bifida, and you will need to take 5mg of folic acid supplements daily, until the 12th week of pregnancy.
Certain medications that are used to treat bipolar disorder can affect whether a woman is able to breastfeed her baby.
It is important to seek advice from your GP, who can assess your condition and medication throughout your pregnancy and postnatal period.
